yes it is possible i've done it by .htaccess Mine looks sth like that: Just create empty file in root folder and paste that in it, then change name to .htaccess
then you must edit all templates and change urls. :) good luck ! now i dont use short urls because i have some problems with adding and deleting from cart :| but it is possible to repair it.
Open your text editor and paste all of the above into a text file and save it called htaccess (depending on your system if you put the (.) dot in front of it it may be hidden) anyway upload the file to the root dir of the QCart
Then add the (.) in front of it using the rename file feature of your ftp client - the server will "see" this (hidden file - especially if you have an Apache based server) as someone loads up your cart in their browser....